Uganda has progressive legislation in place to support the rights of people with disabilities, and it has received donor support over the years for special education and community-based rehabilitation programs. Yet while political mobilization and interventions that aim to minimize disabling conditions have been important, they are not necessarily seen as a means to achieving rights and self-sufficiency. Using examples of families I have known for decades, I show how disability interventions and institutions affect their lives in the long run. James Ferguson’s approach to relations of dependence is useful in understanding how people in eastern Uganda perceive the possibilities in disability projects. I contrast global health time as instantiated in such projects with lifetimes of people and families with disabilities. Humanitarian and development projects sometimes feed into life projects such as education, housing, livelihood, and making families. But their impact is often not so great in the long run of lifetimes intertwined with lives of intimate others.